WIKI4

Supplier MedChemExpress
Product # HY-16910-50 mg
CAS # 838818-26-1
Pricing 50 mg, USD $372.0
Biological Activity WIKI4 is a potent tankyrase inhibitor with an IC50 of 26 nM for TNKS2. WIKI4 potently inhibits Wnt/β-catenin signaling and that its half-maximal response dose is 75 nM. WIKI4 mediates its effects on Wnt/β-catenin signaling by inhibiting the enzymatic activity of TNKS2[1][2]. WIKI4 is cytotoxic to SCLC cells with an IC50 value of 0.02 μM[3].
Purity 99.77%
MWt 521.59
Formula C₂₉H₂₃N₅O₃S
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