Niraparib, p-Toluenesulfonate Salt

Niraparib enhanced radiation-induced cytotoxicity in neuroblastoma cells.  In vivo treatment with niraparib and radiation prolonged survival of mice in a murine xenograft model of metastatic neuroblastoma when compared to single modalities.  Mueller S., et al. Poly (ADP-Ribose) polymerase inhibitor MK-4827 together with radiation as a novel therapy for metastatic neuroblastoma." Anticancer Res. 33: 755-762 (2013)."

• Supplier: LC Laboratories
• Product #: N-5688
• Sku #: N-5688_25mg