JH-XI-10-02

Supplier MedChemExpress
Product # HY-111518-25 mg
CAS # 2209085-22-1
Pricing 25 mg, USD $4500.0
Biological Activity JH-XI-10-02 is a highly potent and selective PROTAC CDK8 degrader, with an IC50 of 159 nM. JH-XI-10-02 causes proteasomal degradation, does not affect CDK8 mRNA levels. JH-XI-10-02 shows no effect on CDK19[1].
Purity 98.18%
MWt 920.14
Formula C₅₃H₆₉N₅O₉
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