GSK3368715 dihydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-128717A-25 mg |
| CAS # | 1628925-77-8 |
| Pricing | 25 mg, USD $390.0 |
| Synonyms | EPZ019997 dihydrochloride |
| MWt | 439.46 |
| Formula | C₂₀H₄₀Cl₂N₄O₂ |
| Biological Activity | GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)). GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) produces a shift in arginine methylation states, alters exon usage, and has strong anti-cancer activity[1]. |
| Purity | 99.94% |