PD 121373

This active molecular has a Benzothiopyrano-indazole structure and the benzothiopyranoindazoles are potent inhibitors of nucleic acid synthesis, reducing both DNA and RNA synthesis to the same extent at similar concentrations. PD 121373 made DNA single- and double-strand breaks in a time and concentration-dependent manner in L1210 cells. In 2003, PD 121373 was in Phase-II for Colorectal cancer, Solid tumours and Prostate cancer in USA.
Supplier BOC Sciences
Product # 113457-06-0
Pricing Inquire
Cas 113457-06-0
Molecular Weight 397.54
Molecular Formula C21H27N5OS
Canonical SMILES OC1=CC=C(S2)C(C3=NN(CCN(CC)CC)C4=C3C2=C(NCCN)C=C4)=C1
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