PD 121373
This active molecular has a Benzothiopyrano-indazole structure and the benzothiopyranoindazoles are potent inhibitors of nucleic acid synthesis, reducing both DNA and RNA synthesis to the same extent at similar concentrations. PD 121373 made DNA single- and double-strand breaks in a time and concentration-dependent manner in L1210 cells. In 2003, PD 121373 was in Phase-II for Colorectal cancer, Solid tumours and Prostate cancer in USA.
Supplier | BOC Sciences |
---|---|
Product # | 113457-06-0 |
Pricing | Inquire |
Cas | 113457-06-0 |
Molecular Weight | 397.54 |
Molecular Formula | C21H27N5OS |
Canonical SMILES | OC1=CC=C(S2)C(C3=NN(CCN(CC)CC)C4=C3C2=C(NCCN)C=C4)=C1 |