β-Casomorphin (1-2)

Supplier Creative Peptides
Product # C10001
CAS # 51871-47-7
Pricing Inquire
Synonyms beta-Casomorphin (1-2); b-Casomorphin (1-2); L-Tyrosyl-L-proline
MolecularFormula C14H18N2O4
MolecularWeight 278.31
Sequence
  • One Letter Code: YP
  • Three Letter Code: H-Tyr-Pro-OH
Storage Store at -20°C
ShippingCondition
  • Evaluation sample solution : ship with blue ice
  • All other available size: ship with RT , or blue ice upon request
Explanation The antihypertensive peptide isolated from fermented milk had a low inhibitory activity against angiotensin I-converting enzyme (ACE), IC50 720 μM. The dipeptide is a possible biosynthetic precursor of endomorphin.
ChemicalName (2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxylic acid
Activity Inhibitor
InChI InChI=1S/C14H18N2O4/c15-11(8-9-3-5-10(17)6-4-9)13(18)16-7-1-2-12(16)14(19)20/h3-6,11-12,17H,1-2,7-8,15H2,(H,19,20)/t11-,12-/m0/s1
InChIKey VNYDHJARLHNEGA-RYUDHWBXSA-N
CanonicalSMILES C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)O
Solubility Soluble in DMSO
IsomericSMILES C1C[C@H](N(C1)C(=O)[C@H](CC2=CC=C(C=C2)O)N)C(=O)O
Appearance White or off-white lyophilized powder
BiologicalActivity Tyr-Pro is a dipeptide obtained by formal condensation of the carboxy group of L-tyrosine with the amino group of L-proline. It derives from a L-tyrosine and a L-proline.
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