K-Ras ligand-Linker Conjugate 6
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-130991-100 mg |
| CAS # | 2378261-89-1 |
| Pricing | 100 mg, USD $1100.0 |
| Biological Activity | K-Ras ligand-Linker Conjugate 6 incorporates a ligand for K-Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 6 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells[1]. |
| MWt | 788.98 |
| Formula | C₄₂H₆₀N₈O₇ |