DBCO-NHCO-PEG4-amine
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-124386 |
| CAS # | 1255942-08-5 |
| Pricing | inquire |
| Biological Activity | DBCO-NHCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE (HY-15162) and antibody (e.g., DBCO-VCpAB−MMAE and DBCO-TRX−MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively)[1]. |
| MWt | 523.62 |
| Formula | C₂₉H₃₇N₃O₆ |