Nevanimibe hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-100399A-10 mM * 1 mL |
| CAS # | 133825-81-7 |
| Pricing | 10 mM * 1 mL, USD $286.0 |
| Synonyms | PD-132301 hydrochloride; ATR101 hydrochloride |
| MWt | 458.08 |
| Formula | C₂₇H₄₀ClN₃O |
| Biological Activity | Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer[1]. |
| Purity | 98.07% |