BET bromodomain inhibitor 1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-131061 |
| CAS # | 2411226-02-1 |
| Pricing | inquire |
| Biological Activity | BET bromodomain inhibitor 1 is an orally active, selective bromodomain and extra-terminal (BET) bromodomain inhibitor with an IC50 of 2.6 nM for BRD4. BET bromodomain inhibitor 1 binds to BRD2(2), BRD3(2), BRD4(1), BRD4(2), and BRDT(2) with high affinities (Kd values of 1.3 nM, 1.0 nM, 3.0 nM, 1.6 nM, 2.1 nM, respectively). bromodomain inhibitor 1 has anti-cancer activity[1]. |
| MWt | 459.47 |
| Formula | C₂₂H₁₉F₂N₃O₄S |