(+)-ITD-1
(+)-ITD-1 is the (+)-enantiomer of ITD 1 that is more active. ITD-1 is a selective inhibitor of TGFβ/Smad signaling (IC50 values 0.46 μM and 6.90 μM for (+)-ITD 1 and (−)-ITD 1, respectively for TGF-β inhibition) that clears the type II TGFβ receptor from the cell surface. ITD 1 promotes the differentiation of cardiomyocytes and cardiogenesis in murine embryonic stem cell (mESCs).
| Supplier | BOC Sciences |
|---|---|
| Product # | 1409968-46-2 |
| Pricing | Inquire |
| Cas | 1409968-46-2 |
| Molecular Weight | 415.52 |
| Molecular Formula | C27H29NO3 |