Pasireotide

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Supplier	Creative Peptides
Product #	10-101-169
CAS #	396091-73-9
Pricing	Inquire
Synonyms	SOM 230;Pasireotidum
MolecularFormula	C58H66N10O9
MolecularWeight	1047.20624
Source	Synthetic
Sequence	One Letter Code: cyclo((4R)-4-(2-Aminoethylcarbamoyloxy)-LPFWK-4-O-benzyl-YF-) Three Letter Code: cyclo((4R)-4-(2-Aminoethylcarbamoyloxy)-L-Pro-L-Phe-D-Trp-L-Lys-4-O-benzyl-L-Tyr-L- Phe-)
Storage	-20°C
ShippingCondition	Room temperature
Explanation	Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor®, which is used in the treatment of Cushing's disease.
Application	Pasireotide is used for the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery has not been curative or is not an option.
InChI	InChI=1S/C58H66N10O9/c59-27-13-12-22-46-52(69)64-47(30-38-23-25-42(26-24-38)76-36-39-16-6-2-7-17-39)53(70)66-49(31-37-14-4-1-5-15-37)57(74)68-35-43(77-58(75)61-29-28-60)33-50(68)55(72)67-51(40-18-8-3-9-19-40)56(73)65-48(54(71)63-46)32-41-34-62-45-21-11-10-20-44(41)45/h1-11,14-21,23-26,34,43,46-51,62H,12-13,22,27-33,35-36,59-60H2,(H,61,75)(H,63,71)(H,64,69)(H,65,73)(H,66,70)(H,67,72)/t43-,46+,47+,48-,49+,50+,51+/m1/s1
InChIKey	VMZMNAABQBOLAK-DBILLSOUSA-N
CanonicalSMILES	C1C(CN2C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C2=O)CC3=CC=CC=C3)CC4=CC=C(C=C4)OCC5=CC=CC=C5)CCCCN)CC6=CNC7=CC=CC=C76)C8=CC=CC=C8)OC(=O)NCCN
IsomericSMILES	C1[C@H](CN2[C@@H]1C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C2=O)CC3=CC=CC=C3)CC4=CC=C(C=C4)OCC5=CC=CC=C5)CCCCN)CC6=CNC7=CC=CC=C76)C8=CC=CC=C8)OC(=O)NCCN

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