NS8593 hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-110105-10 mM * 1 mL |
| CAS # | 875755-24-1 |
| Pricing | 10 mM * 1 mL, USD $110.0 |
| Biological Activity | NS8593 hydrochloride is a potent and selective small conductance Ca2+-activated K+ channels (SK channels) inhibitor. NS8593 hydrochloride reversibly inhibits SK3-mediated currents with a Kd value of 77 nM. NS8593 hydrochloride inhibits all the SK1-3 subtypes Ca2+-dependently (Kds of 0.42, 0.60, and 0.73 μM, respectively, at 0.5 μM Ca2+), and does not affect the Ca2+-activated K+ channels of intermediate and large conductance (hIK and hBK channels, respectively)[1][2]. |
| Purity | 99.88% |
| MWt | 299.8 |
| Formula | C₁₇H₁₈ClN₃ |