Recombinant Camel Anti-KRAS (G12D) Single Domain Antibody (KRAS 13)
Anti-KRAS scAbs were developed to target wild type and mutated KRAS (G12D) in order to disrupt its role in malignant cells, such as cells involved in col orectal cancer, pancreatic cancer, biliary tract cancer, lung cancer, leukemias, and other metastatic malignancies. With out being bound by a particular mechanism, it is thought that the anti-KRAS scAb binds KRAS and blocks the down stream signaling of KRAS in malignant cells. Additionally, the anti-KRAS saAb may successfully treat malignancies that are resistant to anti-EGFR biologics (e.g., cetuximab and panitumumab).
| Supplier | Creative Biolabs |
|---|---|
| Product # | HPAB-AP503-YC |
| Pricing | Inquiry |
| Host | Camel |
| Target | KRAS (G12D) |
| Species Reactivity | Human |
| Type | Camel VHH |
| Applications | ELISA, Block, Cytotoxicity |
| Storage | Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles |