Vandetanib hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10260B |
| CAS # | 524722-52-9 |
| Pricing | inquire |
| Biological Activity | Vandetanib hydrochloride (D6474 hydrochloride) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib hydrochloride also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM)[1]. |
| Synonyms | ZD6474 hydrochloride |
| MWt | 511.81 |
| Formula | C₂₂H₂₅BrClFN₄O₂ |