Minichromosome Maintenance Deficient 6 Homolog (MCM6) Antibody

MCM6 Antibody is a Rabbit Polyclonal antibody against MCM6. The MCM genes were firstly identified in yeast defective in minichromosome maintenance and have since been shown to have roles in the progression of the cell cycle, and most of them are cell division control genes[PMID: 18096807]. MCM2-7 complex are suggested to be 'DNA licensing factors' which bind to the DNA after mitosis and enable DNA replication before being removed during S phase. Mini-chromosome maintenance 6 (MCM6) is one component of the MCM2-7 complex which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells[PMID: 9305914]. MCM6 single subunit forms homohexamer and contains an ATP-dependent and replication fork stimulated 3' to 5' DNA unwinding activity along with intrinsic DNA-dependent ATPase and ATP-binding activities [PMID:21336027].
Supplier Abbexa Ltd.
Product # abx001595-200UL
Pricing 200 µl USD $696.0
Clonality Polyclonal
Conjugation Unconjugated
Host Rabbit
Tested Applications WB, IF/ICC, IP
UniProt Primary AC Q14566
Dry Ice No
Availability Shipped within 5-10 working days.
Note This product is for research use only.
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