PHA-543613
PHA-543613 acts as a potent and selective agonist for the α7 subtype of neural nicotinic acetylcholine receptors, with a high level of brain penetration and good oral bioavailability. It is under development as a possible treatment for cognitive deficits in schizophrenia.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1634 |
| CAS # | 478149-53-0 |
| Pricing | Customizable size, Inquiry |
| Synonym | PHA-543613; PHA 543613; PHA543613. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C15H17N3O2 |
| Exact Mass | 271.1321 |
| Molecular Weight | 271.32 |
| Elemental Analysis | C, 66.40; H, 6.32; N, 15.49; O, 11.79 |
| IUPAC/Chemical Name | (R)-N-(Quinuclidin-3-yl)furo(2,3-C)pyridine-5-carboxamide |
| InChi Key | IPKZCLGGYKRDES-ZDUSSCGKSA-N |
| InChi Code | InChI=1S/C15H17N3O2/c19-15(12-7-11-3-6-20-14(11)8-16-12)17-13-9-18-4-1-10(13)2-5-18/h3,6-8,10,13H,1-2,4-5,9H2,(H,17,19)/t13-/m0/s1 |
| SMILES Code | O=C(C1=CC2=C(OC=C2)C=N1)N[C@H]3CN4CCC3CC4 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |