Miransertib hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-19719A |
| CAS # | 1313883-00-9 |
| Pricing | inquire |
| Biological Activity | Miransertib hydrochloride (ARQ-092 hydrochloride) is a potent, orally active, selective and allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively. Miransertib hydrochloride is also a potent the AKT1-E17K mutant protein inhibitor and has the potential for PI3K/AKT-driven tumors and Proteus syndrome research[1]. Miransertib hydrochloride is effective against Leishmania[2]. |
| Synonyms | ARQ-092 hydrochloride |
| MWt | 468.98 |
| Formula | C₂₇H₂₅ClN₆ |