EGFR-IN-11
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-130616-100 mg |
| CAS # | 2463200-44-2 |
| Pricing | 100 mg, USD $3400.0 |
| Biological Activity | EGFR-IN-11 is a fourth-generation EGFR-tyrosine kinase inhibitor (EGFR-TKI) with an IC50 of 18 nM for triple mutant EGFRL858R/T790M/C797S. EGFR-IN-11 significantly suppresses the EGFR phosphorylation, induce the apoptosis, and arrest cell cycle at G0/G1[1]. |
| Purity | 99.81% |
| MWt | 573.71 |
| Formula | C₂₉H₃₅N₉O₂S |