Human Proteasome Subunit Alpha Type 7 (PSMA7) Protein

Proteasome Subunit Alpha Type 7 (PSMA7) is a recombinant enzyme. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the peptidase T1A family that functions as a 20S core alpha subunit. The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity, an activity essential for viral replication. The encoded protein also plays a role in the cellular stress response by regulating hypoxia-inducible factor-1alpha. A pseudogene of this gene is located on the long arm of chromosome 9.

• Supplier: Abbexa Ltd.
• Product #: abx073064-10UG
• Host: E. coli
• Tested Applications: SDS-PAGE
• UniProt Primary AC: O14818
• Activity: Not tested
• Dry Ice: No
• Availability: Shipped within 5-10 working days.
• Note:
  • This product is for research use only.
  • Not for human consumption, cosmetic, therapeutic or diagnostic use.