BMS-1166-N-piperidine-CO-N-piperazine
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-131386 |
| CAS # | 2447066-14-8 |
| Pricing | inquire |
| Biological Activity | BMS-1166-N-piperidine-CO-N-piperazine incorporates a ligand for PD-1/PD-L1 immune checkpoint, and a PROTAC linker. BMS-1166-N-piperidine-CO-N-piperazine can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183). PROTAC PD-1/PD-L1 degrader-1 inhibits PD-1/PD-L1 interaction with an IC50 of 39.2 nM[1]. |
| MWt | 707.26 |
| Formula | C₄₁H₄₃ClN₄O₅ |