Dasatinib hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10181A-500 mg |
| CAS # | 854001-07-3 |
| Pricing | 500 mg, USD $118.0 |
| Synonyms | BMS-354825 hydrochloride |
| MWt | 524.47 |
| Formula | C₂₂H₂₇Cl₂N₇O₂S |
| Biological Activity | Dasatinib (BMS-354825) hydrochloride is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib hydrochloride inhibits Bcr-Abl and Src with IC50s of <1.0 nM and 0.5 nM, respectively[1]. Dasatinib hydrochloride also induces apoptosis and autophagy. |
| Purity | 98.86% |