chloramphenicol O-acetyltransferase
Chloramphenicol acetyltransferase (or CAT) is a bacterial enzyme (EC 2.3.1.28) that detoxifies the antibiotic chloramphenicol and is responsible for chloramphenicol resistance in bacteria. This enzyme covalently attaches an acetyl group from acetyl-CoA to chloramphenicol, which prevents chloramphenicol from binding to ribosomes. A histidine residue, located in the C-terminal section of the enzyme, plays a central role in its catalytic mechanism.
Supplier | Creative Enzymes |
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Product # | EXWM-2205 |
Pricing | 100 ug, contact supplier for pricing |
CAS | 2608021.0 |