Amitifadine free base
Amitifadine, also known as DOV-21,947 or EB-1010, is an antidepressant drug candidate. It is a so-called triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). Amitifadine reduces nicotine self-administration in female rats. Amitifadine reduces binge drinking and negative affect in an animal model of co-occurring alcoholism and depression symptomatology.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD685 |
| CAS # | 410074-73-6 (free base) |
| Pricing | Customizable size, Inquiry |
| Synonym | DOV-21,947; DOV21,947; DOV 21,947; DOV-21947; DOV21947; DOV 21947; EB-1010; EB 1010; EB1010; Amitifadine |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C11H11Cl2N |
| Exact Mass | 227.0269 |
| Molecular Weight | 228.116 |
| Elemental Analysis | C, 57.92; H, 4.86; Cl, 31.08; N, 6.14 |
| IUPAC/Chemical Name | (1R,5S)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane |
| InChi Key | BSMNRYCSBFHEMQ-KCJUWKMLSA-N |
| InChi Code | InChI=1S/C11H11Cl2N/c12-9-2-1-7(3-10(9)13)11-4-8(11)5-14-6-11/h1-3,8,14H,4-6H2/t8-,11+/m1/s1 |
| SMILES Code | ClC1=CC=C([C@]23CNC[C@@]2([H])C3)C=C1Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |