NONcNZO10/LtJ Mouse
NONcNZO10/LtJ is a recombinant congenic strain to model human obesity-induced Type 2 diabetes and Metabolic Syndrome. Type 2 diabetes in males of this strain results from polygenic interactions producing a moderate obesity rather than the massive obesity elicited by mutations in the leptin/leptin receptor axis. Unlike mice with monogenic obesity syndromes, NONcNZO10/LtJ males do not exhibit hypercorticism, are not hyperphagic, and show no obvious thermoregulatory defects.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | DMM-001007 |
| Pricing | Inquiry |
| Category | Mouse Models |
| disease type | T2DM |
| Strain Name | NONcNZO10/LtJ |
| Background Strain | NON/Lt |
| SPF | Yes |
| Research Application | Diabetes |