Phospho-c-Jun (Ser73) Antibody
| Supplier | CD BioSciences |
|---|---|
| Product # | AMA-0230 |
| Pricing | 100 µg, Inquire |
| Product Category | Antibodies |
| Application | WB, IHC |
| Product Usage Information Dilution | Western Blotting (1 µg/mL); Immunohistochemistry (10-20 µg/mL) |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Gene ID | 3725 |
| Source/Isotype | Rabbit IgG |
| Storage | Store at -20°C. |
| Purification | Affinity purified |
| Background | c-Jun is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals, such as growth factors and UV irradiation, stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. The MAP kinase homologue, SAPK/JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. |