Tumor Necrosis Factor-α human

Tumor necrosis factor-α (TNF-α) is a mononuclear macrophage-derived cytokine with in vivo anti-tumor properties and in vitro cytotoxicity to some transformed cell lines. TNF-α is a bifunctional growth regulator that can promote the growth of a variety of cells. TNF-α belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-α is a pleiotropic pro-inflammatory cytokine that plays a role in antitumor activity, immunomodulation, inflammation, anorexia, cachexia, septic shock, viral replication, and hematopoiesis.

• Supplier: BOC Sciences
• Product #: BAT-015208
• Cas: 94948-59-1
• Molecular Weight: ~17.4 kDa