Recombinant Human PRAME Protein, His-tagged
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
Supplier | Creative Biomart |
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Product # | PRAME-723H |
Pricing | 10ug : USD $298 |