Panamesine
Panamesine is a sigma receptor antagonist that was under development by Merck as a potential antipsychotic for the treatment of schizophrenia in the 1990s but was never marketed. It is a selective antagonist of both sigma receptor subtypes, the σ₁ and σ₂ receptors.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1619 |
| CAS # | 139225-22-2 |
| Pricing | Customizable size, Inquiry |
| Synonym | Panamesine |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C23H26N2O6 |
| Exact Mass | 426.1791 |
| Molecular Weight | 426.47 |
| Elemental Analysis | C, 64.78; H, 6.15; N, 6.57; O, 22.51 |
| IUPAC/Chemical Name | (5S)-5-((4-Hydroxy-4-(3,4-(methylenedioxy)phenyl)piperidino)methyl)-3-(p-methoxyphenyl)-2-oxazolidinone. |
| InChi Key | NINYZUDVKTUKIA-IBGZPJMESA-N |
| InChi Code | InChI=1S/C23H26N2O6/c1-28-18-5-3-17(4-6-18)25-14-19(31-22(25)26)13-24-10-8-23(27,9-11-24)16-2-7-20-21(12-16)30-15-29-20/h2-7,12,19,27H,8-11,13-15H2,1H3/t19-/m0/s1 |
| SMILES Code | O=C1O[C@@H](CN2CCC(C3=CC(OCO4)=C4C=C3)(O)CC2)CN1C5=CC=C(OC)C=C5 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | To be determined |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | To be determined |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |