PGC-1alpha Antibody
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may also be involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
Supplier | Creative Biogene |
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Product # | PBCA1034 |
Pricing | Inquiry |
Isotype | Rabbit IgG |
Research Area | Antibody |
Antibody Target | PGC-1alpha |
Antibody Type | Polyclonal |
Application | WB |
Formulation | 0.5 mg/ml of antibody in PBS, pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal |
Appearance | Liquid |
Host | Rabbit |
Species Reactivity | Human, Mouse, Rat |
Usage Statement | Our products are intended for research use only and are not to be used for other purposes, including but are not limited to in vitro diagnostic uses, ex vivo or in vivo therapeutic uses. |