3-MA (3-Methyladenine)
3-MA (3-Methyladenine) is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM in HeLa cells; blocks class I PI3K consistently, whereas suppression of class III PI3K is transient, and also blocks autophagosome formation. Solutions are unstable and should be fresh-prepared.
| Supplier | Selleck Chemicals |
|---|---|
| Product # | S2767 |
| Sku # | S2767-2g |
| Pricing | 2g, $790.00 |
Citations for this product:
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bioRxiv - Cell Biology 2021Quote: ... 3-Methyladenine (S2767, 5mM) and Bafilomycin A1 (S1413, 100 nM) were purchased from Selleck Chemicals and incubated for 24h prior to imaging or cell harvesting ...