DL-TBOA ammonium
DL-TBOA ammonium is a potent non-transportable EAATs inhibitor with IC50s of 70, 6 and 6 μM for excitatory amino acid transporter-1 (EAAT1), EAAT2 and EAAT3, respectively. It competitively blocks EAAT4 and EAAT5 with Kis of 4.4 and 3.2 μM, respectively. It inhibits the uptake of [14C]glutamate in COS-1 cells expressing the human EAAT1 and EAAT2 with Kis of 42 and 5.7 μM, respectively.
| Supplier | BOC Sciences |
|---|---|
| Product # | 2093503-71-8 |
| Pricing | Inquire |
| Cas | 2093503-71-8 |
| Molecular Weight | 256.26 |
| Molecular Formula | C11H16N2O5 |
| Canonical SMILES | C1=CC=C(C=C1)COC(C(C(=O)O)N)C(=O)O.N |