γ-Glu-Cys

Supplier Creative Peptides
Product # CP27730
CAS # 636-58-8
Pricing Inquire
Synonyms Gamma-L-glutamyl-L-cysteine; gamma-Glu-Cys; gamma-Glutamylcysteine
MolecularFormula C8H14N2O5S
MolecularWeight 250.27
Sequence H-γ-Glu-Cys-OH
Storage Store at -20°C
ShippingCondition Evaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
Explanation Substrate used for the biosynthesis of L-glutathione by glutathione synthetase(s)
ChemicalName (2S)-2-amino-5-[[(1R)-1-carboxy-2-sulfanylethyl]amino]-5-oxopentanoic acid
Application Di- and Tripeptides
InChI InChI=1S/C8H14N2O5S/c9-4(7(12)13)1-2-6(11)10-5(3-16)8(14)15/h4-5,16H,1-3,9H2,(H,10,11)(H,12,13)(H,14,15)/t4-,5-/m0/s1
InChIKey RITKHVBHSGLULN-WHFBIAKZSA-N
CanonicalSMILES C(CC(=O)NC(CS)C(=O)O)C(C(=O)O)N
Solubility ≥25mg/mL in H2O, ≥52 mg/mL in DMSO, ≥54.8 mg/mL in EtOH
IsomericSMILES C(CC(=O)N[C@@H](CS)C(=O)O)[C@@H](C(=O)O)N
BiologicalActivity γ-Glu-Cys is produced by cleaving the Cys-Gly peptide bond of glutathione. It is also necessary for the formation of phytochelins, which are cysteine-rich thiol-reactive peptides.
Reference 1. Anjum N A, Gill S S, Gill R, et al. Plant adaptation to environmental change: significance of amino acids and their derivatives. 2014.
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