7-Hydroxymethotrexate
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-130569 |
| CAS # | 5939-37-7 |
| Pricing | inquire |
| Biological Activity | 7-Hydroxymethotrexate is a major metabolite of Methotrexate (MTX; HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis[1][2]. |
| MWt | 470.44 |
| Formula | C₂₀H₂₂N₈O₆ |