JNJ-37822681
JNJ-37822681 is a novel, potent, specific, centrally active, and fast-dissociating D(2) antagonist with optimal brain disposition. JNJ-37822681 is the first compound that allows the evaluation of the potential value of fast D(2) antagonism for the treatment of schizophrenia and bipolar disorder.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD539 |
| CAS # | 935776-74-2 |
| Pricing | Customizable size, Inquiry |
| Synonym | JNJ-37822681; JNJ 37822681; JNJ37822681. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C17H17F5N4 |
| Exact Mass | 372.13734 |
| Molecular Weight | 372.34 |
| Elemental Analysis | C, 54.84; H, 4.60; F, 25.51; N, 15.05 |
| IUPAC/Chemical Name | 3-Pyridazinamine, N-(1-((3,4-difluorophenyl)methyl)-4-piperidinyl)-6-(trifluoromethyl)- |
| InChi Key | UVUYWJWYRLJHEN-UHFFFAOYSA-N |
| InChi Code | 1S/C17H17F5N4/c18-13-2-1-11(9-14(13)19)10-26-7-5-12(6-8-26)23-16-4-3-15(24-25-16)17(20,21)22/h1-4,9,12H,5-8,10H2,(H,23,25) |
| SMILES Code | FC(C1=NN=C(NC2CCN(CC3=CC=C(F)C(F)=C3)CC2)C=C1)(F)F |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Class-2 | Schizophrenia |