Jasplakinolide
Jasplakinolide acts as an actin stabilizing agent that stabilizes actin filaments and promotes actin polymerization. It is also a potent inhibitor of breast and prostrate carcinoma cell proliferation. It potently competes with phalloidin for actin binding and induces actin polymerization by stimulating actin filament nucleation in vitro. It induces polymerization of monomeric actin into amorphous masses and disrupts actin filaments in vivo. It is cell permeable and affects chromosome movement in studies. It has insecticidal, antiproliferative and fungicidal activity. It is useful for investigating cell processes mediated by actin depolymerization and polymerization.
| Supplier | BOC Sciences |
|---|---|
| Product # | 102396-24-7 |
| Pricing | Inquire |
| Cas | 102396-24-7 |
| Molecular Weight | 709.67 |
| Molecular Formula | C36H45BrN4O6 |
| Canonical SMILES | CC1CC(OC(=O)CC(NC(=O)C(N(C(=O)C(NC(=O)C(CC(=C1)C)C)C)C)CC2=C(NC3=CC=CC=C32)Br)C4=CC=C(C=C4)O)C |