Recombinant Human Anti-gD protein Antibody (CH-42)
Provided are anti-HSV gD antibodies derived from a vaccinated human subject and rescued using recombinant DNA techniques. The antibodies specific for gD of HSV. CH42_HC_AAA has a unique amino acid sequence. The constant region sequence of CH42 is IgA2-IgGl_AAA chimeric -the original CH42 heavy chain was IgA2. Assay results show that amino acid substitutions at positions 12-16 (ADPNR = alanine -aspartic acid -proline -asparagine -arginine) reduce binding to near background. Substitution of the aspartic acid at position 6 also results in some reduction in binding.
| Supplier | Creative Biolabs |
|---|---|
| Product # | HPAB-N0100-YC |
| Pricing | Inquiry |
| Host | Human |
| Target | gD protein |
| Species Reactivity | HSV |
| Type | Human IgG |
| Applications | ELISA, Neutralization |