Alosetron Hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-70050C-10 mg |
| CAS # | 122852-69-1 |
| Pricing | 10 mg, USD $51.0 |
| Synonyms | GR 68755C; GR 68755 Hydrochloride; GR 68755X Hydrochloride |
| MWt | 330.81 |
| Formula | C₁₇H₁₉ClN₄O |
| Biological Activity | Alosetron Hydrochloride (GR 68755C) is a potent and highly selective serotonin 5-HT3 receptor antagonist. Alosetron Hydrochloride is used for the research of irritable bowel syndrome (IBS). Alosetron blocks the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons, with IC50 at ~55 nM. Alosetron Hydrochloride attenuates the visceral nociceptive effect of rectal distension in conscious or anaesthetised dogs. Anti-inflammatory effects[1][2]. |
| Purity | 99.79% |