Pico145
Supplier | MedChemExpress |
---|---|
Product # | HY-101507-10 mg |
CAS # | 1628287-16-0 |
Pricing | 10 mg, USD $550.0 |
Synonyms | HC-608 |
MWt | 524.88 |
Formula | C₂₃H₂₀ClF₃N₄O₅ |
Biological Activity | Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels, inhibits (−)-englerin A-activated TRPC4/TRPC5 channels, with IC50s of 0.349 and 1.3 nM in cells, and shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8[1]. |
Purity | 98.62% |