GDC-0077

Supplier MedChemExpress
Product # HY-101562-25 mg
CAS # 2060571-02-8
Pricing 25 mg, USD $1260.0
Synonyms RG6114
MWt 407.37
Formula C₁₈H₁₉F₂N₅O₄
Biological Activity GDC-0077 (RG6114) is a potent, orally available, and selective PI3Kα inhibitor (IC50=0.038 nM). GDC-0077 (RG6114) exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3. GDC-0077 (RG6114) is more selective for mutant versus wild-type PI3Kα[1].
Purity 98.94%
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