GSK-25
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-14362-10 mg |
| CAS # | 874119-56-9 |
| Pricing | 10 mg, USD $178.0 |
| Biological Activity | GSK-25 is a potent, selective and orally bioavailable ROCK1 inhibitor (IC50=7 nM). GSK-25 maintains good selectivity against a panel of 31 kinases (>100 fold), as well as RSK1 and p70S6K (RSK1: IC50=398 nM, p70S6K: IC50=1 μM). GSK-25 inhibits P450 profile (IC50s of 2.5, 5.2, 2.5 µM for CYP2C9, CYP2D6, CYP3A4, respectively)[1]. |
| Purity | 99.68% |
| MWt | 513.33 |
| Formula | C₂₄H₁₆Cl₂F₂N₆O |