LY2886721
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13240-5 mg |
| CAS # | 1262036-50-9 |
| Pricing | 5 mg, USD $108.0 |
| Biological Activity | LY2886721 is a potent, selective and orally active beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 of 20.3 nM for recombinant human BACE1. LY2886721 is selectivity against cathepsin D, pepsin, and renin, but lacking selectivity against BACE2 (IC50 of 10.2 nM). LY2886721 can across blood-brain barrier and has the potential for Alzheimer's disease treatment[1]. |
| Purity | 99.92% |
| MWt | 390.41 |
| Formula | C₁₈H₁₆F₂N₄O₂S |