Ipatasertib-NH2
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-130988 |
| CAS # | 1001382-14-4 |
| Pricing | inquire |
| Biological Activity | Ipatasertib-NH2 (GDC-0068-NH2;RG7440-NH2) is a ligand for target protein AKT for PROTAC, binds to lenalidomide, a ligand of ubiquitin E3 ligase cereblon (CRBN), via a ten-hydrocarbon linker to form INY-03-041 (HY-133120) to degrade AKT[1]. |
| Synonyms | GDC-0068-NH2; RG7440-NH2 |
| MWt | 415.92 |
| Formula | C₂₁H₂₆ClN₅O₂ |