BRL-37344 sodium
BRL37344 is a selective β3-adrenergic receptor agonist originated by GlaxoSmithKline. Ki value is 287nM for β3 receptor, 1750nM for β1 receptor and 1120nM for β2 receptor. BRL37344 can decrease nerve-evoked contractions in human detrusor smooth muscle isolated strips, it can also stimulate fuel oxidation by soleus muscle in vitro. BRL37344 increases glucose transport into L6 myocytes through a mechanism different from that of insulin. But preclinical for Diabetes mellitus was discontinued.
| Supplier | BOC Sciences |
|---|---|
| Product # | 127299-93-8 |
| Pricing | Inquire |
| Cas | 127299-93-8 |
| Molecular Weight | 385.82 |
| Molecular Formula | C19H21ClNNaO4 |
| Canonical SMILES | CC(CC1=CC=C(C=C1)OCC(=O)[O-])NCC(C2=CC(=CC=C2)Cl)O.[Na+] |