SARS-CoV-2 Trimeric Spike 1 Protein Antibody
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Trimeric Spike 1 Protein Antibody is a Mouse Monoclonal Antibody against SARS-CoV-2/COVID-19 Trimeric S1 Protein.
The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.
This antibody is designed to work with saliva patient samples that do not require lysis. It is recommended to use abx024240 as the capture antibody and abx024241 or abx024247 (this antibody) as the detection antibody. This antibody can be mixed with abx024241 in a 1:1 ratio for a synergistic effect that increases sensitivity in ELISA. In an ELISA with TMB substrate, this pair can detect SARS-CoV-2 trimeric spike protein with a sensitivity of approximately 300 pg/ml.
The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.
This antibody is designed to work with saliva patient samples that do not require lysis. It is recommended to use abx024240 as the capture antibody and abx024241 or abx024247 (this antibody) as the detection antibody. This antibody can be mixed with abx024241 in a 1:1 ratio for a synergistic effect that increases sensitivity in ELISA. In an ELISA with TMB substrate, this pair can detect SARS-CoV-2 trimeric spike protein with a sensitivity of approximately 300 pg/ml.
| Supplier | Abbexa Ltd. |
|---|---|
| Product # | abx024247-1MG |
| Pricing | 1 mg USD $2842.0 |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Host | Mouse |
| Tested Applications | ELISA, WB, LF |
| Dry Ice | No |
| Availability | Shipped within 10-20 working days. |
| Note | This product is for research use only. |