Refametinib R enantiomer
Refametinib R enantiomer is a potent, selective and allosteric inhibitor of MEK1/2 in enzyme inhibition assays. It has been reported to inhibit MEK activity and inhibit anchorage-dependent growth. Moreover, it has shown a potent tumor growth inhibition (TGI) in the human A375 and colon carcinoma Colo205 tumor xenograft models.
| Supplier | BOC Sciences |
|---|---|
| Product # | 923032-38-6 |
| Pricing | Inquire |
| Cas | 923032-38-6 |
| Molecular Weight | 572.34 |
| Molecular Formula | C19H20F3IN2O5S |
| Canonical SMILES | COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F |