Magic™ Membrane Protein Mouse Kcna3 (Potassium voltage-gated channel, shaker-related subfamily, member 3)

Kv1.3 is a voltage-gated potassium channel that participates in cellular processes such as neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, apoptosis, cell volume regulation, and T cell stimulation. Kv1.3 channels have been proposed to be crucial in the pathogenesis of multiple sclerosis and other autoimmune diseases Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.

• Supplier: Creative Biolabs
• Product #: MP0022F