KB02-JQ1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-129917-5 mg |
| CAS # | 2384184-44-3 |
| Pricing | 5 mg, USD $950.0 |
| Biological Activity | KB02-JQ1 is a highly selective and PROTAC-based BRD4 degrader (molecular glue), but does not degrade BRD2 or BRD3. KB02-JQ1 promotes BRD4 degradation by covalently modifying DCAF16 (E3 ligase) and can improve the durability of protein degradation in biological systems. JQ1 binds ubiquitin E3 ligase ligand KB02 via a linker to form KB02-JQ1[1]. |
| Purity | 98.29% |
| MWt | 796.76 |
| Formula | C₃₈H₄₃Cl₂N₇O₆S |