biotin-Neurogranin (48-76), human

Supplier Creative Peptides
Product # N20001
Pricing Inquire
MolecularWeight 2644.1
Sequence
  • One Letter Code: Biotin-SGERGRKGPGPGGPGGAGVARGGAGGGPS
  • Three Letter Code: biotin-Ser-Gly-Glu-Arg-Gly-Arg-Lys-Gly-Pro-Gly-Pro-Gly-Gly-Pro-Gly-Gly-Ala-Gly-Val-Ala-Arg-Gly-Gly-Ala-Gly-Gly-Gly-Pro-Ser-OH
Storage This peptide is shipped at ambient temperature. Upon receipt, store lyophilized peptide at –20°C or lower. Reconstituted peptide can be aliquoted and stored at –20°C or lower.
Explanation Neurogranin is a post synaptic protein that is expressed in dendritic cytoplasm. It modulates calcium-mediated signaling pathways and plays critical role in synaptic plasticity. Recently Neurogranin (48-76) was identified as a major neurogranin peptide fragment in human brain and it was found that patients with Alzheimer’s Disease have elevated levels of Neurogranin (48-76) in cerebrospinal fluid.
Reference 1. De Vos A., et.al., Alzh and Dement 4, 1-9 (2015)
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