Supplier |
Creative Peptides |
Product # |
N20001 |
Pricing |
Inquire
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MolecularWeight |
2644.1
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Sequence |
- One Letter Code: Biotin-SGERGRKGPGPGGPGGAGVARGGAGGGPS
- Three Letter Code: biotin-Ser-Gly-Glu-Arg-Gly-Arg-Lys-Gly-Pro-Gly-Pro-Gly-Gly-Pro-Gly-Gly-Ala-Gly-Val-Ala-Arg-Gly-Gly-Ala-Gly-Gly-Gly-Pro-Ser-OH
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Storage |
This peptide is shipped at ambient temperature. Upon receipt, store lyophilized peptide at –20°C or lower. Reconstituted peptide can be aliquoted and stored at –20°C or lower.
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Explanation |
Neurogranin is a post synaptic protein that is expressed in dendritic cytoplasm. It modulates calcium-mediated signaling pathways and plays critical role in synaptic plasticity. Recently Neurogranin (48-76) was identified as a major neurogranin peptide fragment in human brain and it was found that patients with Alzheimer’s Disease have elevated levels of Neurogranin (48-76) in cerebrospinal fluid.
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Reference |
1. De Vos A., et.al., Alzh and Dement 4, 1-9 (2015)
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