TC-S 7005
TC-S 7005 is a potent and selective polo-like kinase 2 (PLK2) inhibitor (IC50 = 4 nM) with selectivity over PLK3 and PLK1 (IC50 = 24 and 214 nM, respectively). TC-S 7005 has been shown to induce mitotic arrest and cell death in HCT 116 colorectal cells.
Supplier | BOC Sciences |
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Product # | 1082739-92-1 |
Pricing | Inquire |
Cas | 1082739-92-1 |
Molecular Weight | 359.38 |
Molecular Formula | C21H17N3O3 |
Canonical SMILES | CC(C1=CC=CC=C1)NC2=NC=C3C(=C2)C(=NO3)C4=CC5=C(C=C4)OCO5 |